High loading of trimethylglycine promotes aqueous solubility of poorly water-soluble cisplatin
نویسندگان
چکیده
منابع مشابه
Effect of hydrotalcite-like compounds on the aqueous solubility of some poorly water-soluble drugs.
A new approach of improving drug dissolution properties is described. This method exploits the property of a carrier owing to the hydrotalcite-type anionic clays (HTlc). HTlc is an inorganic layered solid that lodges anionic compounds among its layers. As HTlc dissolves at acidic pH values (pH < 4), the anions intercalated among the layers are promptly released in the medium. In this article so...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2021
ISSN: 2045-2322
DOI: 10.1038/s41598-021-89144-0